1: 94 percent / 15percent HCl/dioxane / Ambient temperature 2: DCC / tetrahydrofuran / Ambient temperature 3: 1) tBuOK / 1) THF, -50 deg C, 20 min, 2) THF, -30 deg C, 20 min 4: ethyl acetate; diisopropyl ether / 3 h / Ambient temperature 5: H2 / Pd / methanol / 2 h / 760 Torr / Ambient temperature View Scheme

1: 94 percent / 15percent HCl/dioxane / Ambient temperature 2: DCC / tetrahydrofuran / Ambient temperature 3: 1) tBuOK / 1) THF, -50 deg C, 20 min, 2) THF, -30 deg C, 20 min View Scheme