1: With sodium hydride in N,N-dimethyl-formamide T=90°C; 2 h; 2: With hydrogenchloride in water T=110°C; 12 h; 3: With sodium hydroxide in water T=0°C; pH=14;

oxygen; hydrazine hydrate; 7-(trifluoromethyl)-1,10-ethyleneisoalloxazinium chloride in water T=100°C; P=760.051 Torr; 18 h;