2,5-二溴-1H-吡咯-1-羧酸-1,1-二甲基乙酯合成路线 (共 6 条)
反应条件
N-bromosuccinmide in tetrahydrofuran
参考文献
Pinkerton, David M.; Banwell, Martin G.; Willis, Anthony C.
Organic Letters, 2007 , vol. 9, # 24 p. 5127 - 5130
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine Yield given;
参考文献
Chen, Wha; Cava, Michael P.
Tetrahedron Letters, 1987 , vol. 28, # 48 p. 6025 - 6026
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethanol; water; toluene T=100°C; Suzuki-Miyaura cross-coupling; 3 h; Inert atmosphere;
参考文献
Synthesis, , # 23 art. no. Z20010SS, p. 4033 - 4042
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium chloride; sodium carbonate in ethanol; water; toluene T=100°C; Suzuki-Miyaura coupling; 3 h; Inert atmosphere;
参考文献
Organic Letters, , vol. 11, # 8 p. 1801 - 1804
反应条件
n-butyllithium 1.) THF, -78 deg C; Yield given. Multistep reaction;
参考文献
Jones, Philip; Bottomley, Matthew J.; Carfi, Andrea; Cecchetti, Ottavia; Ferrigno, Federica; Lo Surdo, Paola; Ontoria, Jesus M.; Rowley, Michael; Scarpelli, Rita; Schultz-Fademrecht, Carsten; Steinkuehler, Christian
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 11 p. 3456 - 3461
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium chloride; sodium carbonate in ethanol; water; toluene
T=100°C; Suzuki-Miyaura coupling; 3 h; Inert atmosphere;
参考文献
Beaumard, Floriane; Dauban, Philippe; Dodd, Robert H.
Organic Letters, 2009 , vol. 11, # 8 p. 1801 - 1804