3-溴咪唑并[1,2-a]吡嗪-8-胺合成路线 （共 6 条）
反应条件
ammonia in water; isopropyl alcohol T=85°C; 72 h;
参考文献
Schering Corporation
Patent: US2007/117804 A1, 2007 ;
Location in patent: Page/Page column 75 ;
US 20070117804 A1
反应条件
ammonia in tetrahydrofuran; water T=50°C;
参考文献
Sugen, Inc.
Patent: US2004/220189 A1, 2004 ;
Location in patent: Page 22 ;
US 20040220189 A1
反应条件
ammonium hydroxide in tetrahydrofuran
参考文献
Sugen, Inc.
Patent: US2005/9832 A1, 2005 ;
US 20050009832 A1
参考文献
l'Universite de Montpellier I
Patent: US5028605 A1, 1991 ;
反应条件
1: bromine / acetic acid 2: ammonia / ethanol / 5 h / 120 °C View Scheme
参考文献
Bonnet, Pierre A.; Michel, Alain; Laurent, Florence; Sablayrolles, Claire; Rechencq, Eliane; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 18 p. 3353 - 3358
参考文献
Sugen, Inc.
Patent: US2005/9832 A1, 2005 ;
US 20050009832 A1
