4-(3-噻吩)-1H-吡唑-3-羧酸合成路线 （共 4 条）
反应条件
potassium hydroxide T=65°C; 0.5 h;
参考文献
Cativiela, Carlos; Villegas, Maria D. Diaz de; Mayoral, Jose A.; Avenoza, Alberto; Roy, Miguel A.
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 851 - 855
反应条件
1: 65 percent / CH3ONa / Ambient temperature 2: 82 percent / CHCl3 / Ambient temperature 3: 86 percent / BF3*Et2O / CHCl3 / 0.5 h / Heating 4: 62 percent / 10percent methanolic KOH / 0.5 h / 65 °C View Scheme
参考文献
Cativiela, Carlos; Villegas, Maria D. Diaz de; Mayoral, Jose A.; Avenoza, Alberto; Roy, Miguel A.
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 851 - 855
反应条件
1: 82 percent / CHCl3 / Ambient temperature 2: 86 percent / BF3*Et2O / CHCl3 / 0.5 h / Heating 3: 62 percent / 10percent methanolic KOH / 0.5 h / 65 °C View Scheme
参考文献
Cativiela, Carlos; Villegas, Maria D. Diaz de; Mayoral, Jose A.; Avenoza, Alberto; Roy, Miguel A.
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 851 - 855
反应条件
1: 86 percent / BF3*Et2O / CHCl3 / 0.5 h / Heating 2: 62 percent / 10percent methanolic KOH / 0.5 h / 65 °C View Scheme
参考文献
Cativiela, Carlos; Villegas, Maria D. Diaz de; Mayoral, Jose A.; Avenoza, Alberto; Roy, Miguel A.
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 851 - 855
