六氢吡咯并[1,2-a]吡嗪-6-酮合成路线 （共 5 条）
反应条件
1.1: NaH / 1,2-dimethoxy-ethane / 1 h 1.2: 60 percent / 1,2-dimethoxy-ethane / 1 h / 20 °C 2.1: 72 percent / H2 / Pd/C / ethanol / 8 h / 2585.81 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 10 p. 1969 - 1974
反应条件
1.1: butyllithium; diisopropylamine / tetrahydrofuran; hexane / 0.17 h / -78 °C 1.2: 20 percent / tetrahydrofuran; hexane / 1 h / -78 °C 2.1: 93 percent / H2 / Pd/C / ethanol / 24 h / 3620.04 Torr 3.1: 43 percent / 1 h / 200 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 1 p. 71 - 85
反应条件
1: 93 percent / H2 / Pd/C / ethanol / 24 h / 3620.04 Torr 2: 43 percent / 1 h / 200 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 1 p. 71 - 85
参考文献
Scapecchi, Serena; Martini, Elisabetta; Manetti, Dina; Ghelardini, Carla; Martelli, Cecilia; Dei, Silvia; Galeotti, Nicoletta; Guandalini, Luca; Romanelli, Maria Novella; Teodori, Elisabetta
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 1 p. 71 - 85
反应条件
Diethylcarbamazine; triethylamine in dichloromethane
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 24 p. 3469 - 3474
