ammonia in methanol T=0 - 20°C; 2.5 h;

1-ethyl-piperidine; dicyclohexyl-carbodiimide in N,N-dimethyl-formamide 1. 0 deg C, 2 h; 2. room temperature, 12 h;

1.1: dithiothreitol; guanidinium hydrochloride / various solvent(s) / 1 h / 20 °C / pH 8.0 1.2: 100 percent / various solvent(s) / 5 h / 20 °C / pH 8.0 2.1: 84 percent / NH3 / methanol / 2.5 h / 0 - 20 °C View Scheme