溴(4-甲氧基-3-甲基苯基)镁合成路线 (共 5 条)
反应条件
iodine; magnesium in tetrahydrofuran 2 h; Heating;
参考文献
Steele, Melanie; Watkinson, Michael; Whiting, Andrew
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 6 p. 588 - 598
反应条件
1: tetrahydrofuran / Ambient temperature 2: H2SO4 / methanol / 4 h / Heating 3: 4.5 N HCl / Heating View Scheme
参考文献
VanAtten, Mary K.; Ensinger, Carol L.; Chiu, Andrew T.; McCall, Dale E.; Nguyen, Tam T.; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 25 p. 3985 - 3992
参考文献
Saari; Williams; Britcher; Wolf; Kuehl Jr.
Journal of medicinal chemistry, 1967 , vol. 10, # 6 p. 1008 - 1014
反应条件
1: With boric acid trimethyl ester in tetrahydrofuran T=-78 - 20°C; 2: With hydrogenchloride in tetrahydrofuran Further stages.;
参考文献
Steele, Melanie; Watkinson, Michael; Whiting, Andrew
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 6 p. 588 - 598
参考文献
Murata; Goto; Fujiyama; Mishima; Fujio; Tsuno
Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 4 p. 1129 - 1137