sodium hydroxide; N-chloro-succinimide; water in acetonitrile T=0 - 5°C; 2 h; Product distribution / selectivity;

3-chloro-benzenecarboperoxoic acid in methanol; chloroform T=-25 - -20°C;

peracetic acid; sodium carbonate in dichloromethane T=20°C; 20 h;

1: 29.5 percent / potassium hydroxide / dimethylsulfoxide / 336 h / 20 °C 2: 33.5 percent / aq. sodium carbonate; peracetic acid / CH2Cl2 / 20 h / 20 °C View Scheme

1: 75 percent / phosphorus oxychloride / CH2Cl2 / 20 °C 2: 52 percent / CH2Cl2 / 12 h / Heating 3: 69 percent / triethylamine / acetonitrile / 18 h / 20 °C 4: 29.5 percent / potassium hydroxide / dimethylsulfoxide / 336 h / 20 °C 5: 33.5 percent / aq. sodium carbonate; peracetic acid / CH2Cl2 / 20 h / 20 °C View Scheme

1: 52 percent / CH2Cl2 / 12 h / Heating 2: 69 percent / triethylamine / acetonitrile / 18 h / 20 °C 3: 29.5 percent / potassium hydroxide / dimethylsulfoxide / 336 h / 20 °C 4: 33.5 percent / aq. sodium carbonate; peracetic acid / CH2Cl2 / 20 h / 20 °C View Scheme

1: 52 percent / triethylamine / acetonitrile / 20 °C 2: 29.5 percent / potassium hydroxide / dimethylsulfoxide / 336 h / 20 °C 3: 33.5 percent / aq. sodium carbonate; peracetic acid / CH2Cl2 / 20 h / 20 °C View Scheme

sodium hydroxide in methanol T=0 - 50°C; 4 - 5 h; Product distribution / selectivity;