3: 98 percent / periodic acid, ruthenium trichloride hydrate / acetonitrile; CCl4; H2O / 2 h 4: diisopropylethylamine, diethylphosphoryl cyanide / CH2Cl2 / 14 h / Ambient temperature 5: acetyl chloride, ethanedithiol / methanol / 5 h 6: diisopropylethylamine, (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / CH2Cl2 / 14 h 7: trifluoroacetic acid / CH2Cl2 / 0.25 h View Scheme

3: 98 percent / periodic acid, ruthenium trichloride hydrate / acetonitrile; CCl4; H2O / 2 h 4: diisopropylethylamine, diethylphosphoryl cyanide / CH2Cl2 / 14 h / Ambient temperature 5: acetyl chloride, ethanedithiol / methanol / 5 h 6: diisopropylethylamine, (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / CH2Cl2 / 14 h 7: trifluoroacetic acid / CH2Cl2 / 0.25 h View Scheme

3: 98 percent / periodic acid, ruthenium trichloride hydrate / acetonitrile; CCl4; H2O / 2 h 4: diisopropylethylamine, diethylphosphoryl cyanide / CH2Cl2 / 14 h / Ambient temperature 5: acetyl chloride, ethanedithiol / methanol / 5 h 6: diisopropylethylamine, (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / CH2Cl2 / 14 h View Scheme

2: aq. hydrogen peroxide, aq. lithium hydroxide / methanol / 4 h / Ambient temperature 3: 1.) camphorsulfonic acid, 2.) acetone / 1.) CH2Cl2, RT, 45 min, 2.) CH2Cl2, RT, 14 h 4: diisopropylethylamine, diethylphosphoryl cyanide / CH2Cl2 / 14 h / Ambient temperature 5: acetyl chloride, ethanedithiol / methanol / 5 h 6: diisopropylethylamine, (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / CH2Cl2 / 14 h 7: trifluoroacetic acid / CH2Cl2 / 0.25 h View Scheme

3: 98 percent / periodic acid, ruthenium trichloride hydrate / acetonitrile; CCl4; H2O / 2 h 4: diisopropylethylamine, diethylphosphoryl cyanide / CH2Cl2 / 14 h / Ambient temperature 5: acetyl chloride, ethanedithiol / methanol / 5 h 6: diisopropylethylamine, (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / CH2Cl2 / 14 h 7: trifluoroacetic acid / CH2Cl2 / 0.25 h View Scheme

Multi-step reaction with 3 steps 3: 98 percent / periodic acid, ruthenium trichloride hydrate / acetonitrile; CCl4; H2O / 2 h