1,3,3-三甲基-2-亚甲基吲哚啉合成路线 （共 94 条）
反应条件
T=110°C; 0.2 h; microwave irradiation;
参考文献
Koshkin; Fedorova; Lokshin; Guglielmetti; Hamelin; Texier-Boullet; Gromov
Synthetic Communications, 2004 , vol. 34, # 2 p. 315 - 322
反应条件
1: 1-nitroso-2-hydroxy-naphthalene; 1-aza-15-crown-5 in methanol T=80°C; 6 h; 2: 1,3-dihydro-1,3,3-trimethyl-2-methyleneindoline in methanol T=80°C; 2.5 h;
参考文献
Fedorova, Olga A.; Strokach, Yuri P.; Gromov, Sergey P.; Koshkin, Alexander V.; Valova, Tatjana M.; Alfimov, Michael V.; Feofanov, Alexei V.; Alaverdian, Iouri S.; Lokshin, Vladimir A.; Samat, Andre; Guglielmetti, Robert; Girling, Reuben B.; Moore, John N.; Hester, Ronald E.
New Journal of Chemistry, 2002 , vol. 26, # 9 p. 1137 - 1145
反应条件
1: 26 percent / Et3N; DMSO / toluene / 20 h / 20 °C 2: methanol / Heating View Scheme
参考文献
Koshkin; Lokshin; Samat; Gromov; Fedorova
Synthesis, 2005 , # 11 art. no. Z21004SS, p. 1876 - 1880
反应条件
1: 1-aza-18-crown-6; 1-nitroso-2-hydroxy-naphthalene in methanol 2: 1,3-dihydro-1,3,3-trimethyl-2-methyleneindoline With triethylamine in methanol Further stages.;
参考文献
Fedorova, Olga A.; Strokach, Yuri P.; Gromov, Sergey P.; Koshkin, Alexander V.; Valova, Tatjana M.; Alfimov, Michael V.; Feofanov, Alexei V.; Alaverdian, Iouri S.; Lokshin, Vladimir A.; Samat, Andre; Guglielmetti, Robert; Girling, Reuben B.; Moore, John N.; Hester, Ronald E.
New Journal of Chemistry, 2002 , vol. 26, # 9 p. 1137 - 1145
反应条件
in tetrahydrofuran T=22°C; 504 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Reichardt, Christian; Engel, Horst-Detlef
Chemische Berichte, 1988 , vol. 121, p. 1009 - 1012
反应条件
in diethyl ether byproducts: CC(CH3)2C6H4N(CH3)CHC(C6H5)CHC(OC2H5), CH2C(C6H5)C(CHO)CC(CH3)2C6H4N(CH3); under Ar; a soln. of the indoline in (CH3CH2)2O was added to W complex, the mixt. was stirred for 1 h at 25°C; the ratio of the products is depended on the solvent; the mixt. was chromd. (fast chromy, Al2O3, n-pentane/(CH3CH2)2O), the cross-conjugated metallatriene was crystd. from (CH3CH2)2O at -40°C; elem. anal.;
参考文献
Organometallics, , vol. 20, # 13 p. 2889 - 2904
反应条件
in diethyl ether byproducts: CC(CH3)2C6H4N(CH3)CHC(Si(CH3)3)CHC(OC2H5); under Ar; a soln. of the indoline in (CH3CH2)2O was added to W complex, the mixt. was stirred for 30 min at 20°C; the mixt. was evapd. and chromd. (fast chromy, Al2O3, n-pentane/(CH3CH2)2O);
参考文献
Goettker-Schnetmann; Aumann, Rudolf; Kataeva, Olga; Holst, Christiane; Froehlich, Roland
Organometallics, 2001 , vol. 20, # 13 p. 2889 - 2904
反应条件
NaY zeolite in dichloromethane
4 h; Heating;
参考文献
Casades; Alvaro; Garcia; Espla
Chemical Communications, 2001 , # 11 p. 982 - 983
反应条件
Catalyst M-Chromium oxide; sulfuric acid
参考文献
Ciamician; Piccinini
Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, 1896 , vol. <5> 5 II, p. 51,55
Chemische Berichte, 1896 , vol. 29, p. 2466
参考文献
Kuhn et al.
Chemische Berichte, 1930 , vol. 63, p. 3176,3182
