3,4,5-三甲氧基苯甲酸合成路线 （共 210 条）
反应条件
1: oxalyl dichloride 2: acetone / 0.33 h / Inert atmosphere; Reflux 3: acetone / 1 h / Inert atmosphere; Reflux View Scheme
参考文献
Solinas, Antonio; Faure, Helene; Roudaut, Hermine; Traiffort, Elisabeth; Schoenfelder, Angele; Mann, Andre; Manetti, Fabrizio; Taddei, Maurizio; Ruat, Martial
Journal of Medicinal Chemistry, 2012 , vol. 55, # 4 p. 1559 - 1571
反应条件
1,1,2-trichloroethylene; potassium carbonate
参考文献
Di Paco; Tauro
Farmaco, Edizione Scientifica, 1958 , vol. 13, p. 429,433
反应条件
1: water containing CHCl3; bromine 2: copper-powder; aqueous NH3 View Scheme
参考文献
Zhang, Zhichao; Liang, Xiaomeng; Li, Xiangqian; Song, Ting; Chen, Qingbin; Sheng, Hongkun
European Journal of Medicinal Chemistry, 2013 , vol. 69, p. 711 - 718
反应条件
diphenylphosphoranyl azide; triethylamine in toluene T=65°C; 2.5 h;
参考文献
Takahashi, Rintaro; Nunokawa, Tatsuya; Shibuya, Tadahiro; Tomita, Ryohei; Tatewaki, Yoko; Okada, Shuji; Kimura, Tatsumi; Shimada, Satoru; Matsuda, Hiro
Bulletin of the Chemical Society of Japan, 2012 , vol. 85, # 2 p. 236 - 244
反应条件
sulfuric acid 3 h; Heating;
参考文献
Choshi; horimoto; Wang; Nagase; Ichikawa; Sugino; Hibino
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 4 p. 1047 - 1049
反应条件
in various solvent(s) T=80°C; 4.5 h;
参考文献
Yoshino, Tomonori; Imori, Satomi; Togo, Hideo
Tetrahedron, 2006 , vol. 62, # 6 p. 1309 - 1317
反应条件
1: 5.8 g / HCl(g) / 5 °C 2: KMnO4 3: xylene / Heating View Scheme
参考文献
Duggal, J. Kaur; Misra, K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1980 , vol. 19, # 11 p. 1000 - 1001
反应条件
triethylamine; phenyl N-phenylphosphoroamidochloridate in dichloromethane 1 h; Ambient temperature;
参考文献
Mestres, Ramon; Palomo, Claudio
Synthesis, 1981 , # 3 p. 218 - 220
反应条件
in chloroform T=20°C; 24 h;
参考文献
Chechulina, L. A.; Puchkova, S. M.; Novikova, A. P.; Baskakova, Z. M.; Vysokov, V. I.; Afanas'eva, G. B.
Pharmaceutical Chemistry Journal, 1985 , vol. 19, # 3 p. 182 - 186
Khimiko-Farmatsevticheskii Zhurnal, 1985 , vol. 19, # 3 p. 168 - 172
反应条件
quinoline; chloroform
参考文献
Fischer,E.; Freudenberg
Chemische Berichte, 1913 , vol. 46, p. 1126,1128
