反应条件
1: 1) Mg, 1,2-Dibromoethane / 1) in THF under refluxtemp., 2) under cooling, 45 min -> 12 h, refluxtemp.
2: 94 percent / PBr3, Py. / benzene / 2 h
3: 89 percent / methanol / 2.5 h / Heating
4: 1) Mg turnings, 1,2-dibromoethane / 1) in THF, 6-8 h, under reflux, 2) in THF, 1 h, 20 deg C -> 1h, reflux
5: 94 percent / NaBH4 / trifluoroacetic acid / 0.25 h / 0 °C
View Scheme
参考文献
Mitchell, Reginald H.; Lai, Yee-Hing
Journal of Organic Chemistry, 1984 , vol. 49, # 14 p. 2534 - 2540
