4-氯-3,5-二硝基苯甲酸合成路线 （共 31 条）
反应条件
[Au(1,3-bis(2,6-diisopropylphenyl)-4,5-dihydroimidazol-2-ylidene)(O2CAd)] in N,N-dimethyl acetamide T=165°C; 48 h;
参考文献
Dupuy, Stephanie; Nolan, Steven P.
Chemistry - A European Journal, 2013 , vol. 19, # 42 p. 14034 - 14038
参考文献
Eli Lilly and Company
Patent: US4024142 A1, 1977 ;
反应条件
1: benzene; PCl5 2: concentrated ammonia View Scheme
参考文献
Lindemann; Wessel
Chemische Berichte, 1925 , vol. 58, p. 1230
参考文献
Smith
Journal of the American Chemical Society, 1949 , vol. 71, p. 2855
反应条件
in methanol 3 h; Heating;
参考文献
George, Tesmol G.; Johnsamuel, Jayaseharan; Delfin, Dawn A.; Yakovich, Adam; Mukherjee, Mitali; Phelps, Mitch A.; Dalton, James T.; Sackett, Dan L.; Kaiser, Marcel; Brun, Reto; Werbovetz, Karl A.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 16 p. 5699 - 5710
反应条件
sulfuric acid in methanol
参考文献
The Upjohn Company
Patent: US3993679 A1, 1976 ;
反应条件
sulfuric acid 5 h; Heating / reflux;
参考文献
AstraZeneca AB; NPS PHARMACEUTICALS
Patent: US2007/32469 A1, 2007 ;
Location in patent: Page/Page column 37-38 ;
US 20070032469 A1
反应条件
sulfuric acid in methanol
参考文献
Budapesti Vegyimuvek
Patent: US4806151 A1, 1989 ;
反应条件
in diethyl ether T=0°C; 12 h;
参考文献
Benbow, John W.; Bernberg, Erin L.; Korda, Anna; Mead, Jan R.
Antimicrobial Agents and Chemotherapy, 1998 , vol. 42, # 2 p. 339 - 343
参考文献
Cheng, Cliff C.; Shipps Jr., Gerald W.; Yang, Zhiwei; Sun, Binyuan; Kawahata, Noriyuki; Soucy, Kyle A.; Soriano, Aileen; Orth, Peter; Xiao, Li; Mann, Paul; Black, Todd
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 23 p. 6507 - 6514
