3-甲氧基-4-(三甲基甲硅烷基)吡啶合成路线 （共 3 条）
反应条件
1: 3-methoxy pyridine With (trimethyl)silylmethyllithium in tetrahydrofuran T=-20°C; 1 h; 2: chloro-trimethyl-silane in tetrahydrofuran T=-20 - 20°C;
参考文献
FMC CORPORATION
Patent: WO2004/92125 A2, 2004 ;
Location in patent: Page 8 ;
反应条件
1: 70 percent / dimethylsulfoxide / 4 h / 120 °C 2: 33 percent / 1.) lithium diisopropylamide / 1.) THF, -42 deg C, 1 h; 2.) THF, -42 deg C, 1 h View Scheme
参考文献
Comins, Daniel L.; LaMunyon, Donald H.
Tetrahedron Letters, 1988 , vol. 29, # 7 p. 773 - 776
反应条件
lithium diisopropyl amide 1.) THF, -42 deg C, 1 h; 2.) THF, -42 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Comins, Daniel L.; LaMunyon, Donald H.
Tetrahedron Letters, 1988 , vol. 29, # 7 p. 773 - 776
