7-氰基-4-羟基-3-喹啉羧酸合成路线 （共 6 条）
反应条件
sodium hydroxide in water 0.5 h; Reflux;
参考文献
Nsumiwa, Samkele; Kuter, David; Wittlin, Sergio; Chibale, Kelly; Egan, Timothy J.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 13 p. 3738 - 3748
参考文献
Dainippon Pharmaceutical Co., Ltd.
Patent: US4965266 A1, 1990 ;
反应条件
1: 0.75 h / 110 °C 2: diphenylether / 1 h / |Reflux 3: sodium hydroxide / water / 0.5 h / |Reflux View Scheme
参考文献
Nsumiwa, Samkele; Kuter, David; Wittlin, Sergio; Chibale, Kelly; Egan, Timothy J.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 13 p. 3738 - 3748
反应条件
1: diphenylether / 1 h / |Reflux 2: sodium hydroxide / water / 0.5 h / |Reflux View Scheme
参考文献
Nsumiwa, Samkele; Kuter, David; Wittlin, Sergio; Chibale, Kelly; Egan, Timothy J.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 13 p. 3738 - 3748
反应条件
in diphenylether 1 h; Reflux;
参考文献
Nsumiwa, Samkele; Kuter, David; Wittlin, Sergio; Chibale, Kelly; Egan, Timothy J.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 13 p. 3738 - 3748
反应条件
in diphenylether 1 h; Reflux;
参考文献
Nsumiwa, Samkele; Kuter, David; Wittlin, Sergio; Chibale, Kelly; Egan, Timothy J.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 13 p. 3738 - 3748
