3-羟基-3-(三氟甲基)环己烯合成路线 （共 3 条）
反应条件
N-(EtOCH2CH2OCH2)-N-methylmorpholinium bis(CF3SO2)amide; cesium fluoride T=25°C; 0.5 h;
参考文献
Kim, Jinwi; Shreeve, Jean'ne M.
Organic and Biomolecular Chemistry, 2004 , vol. 2, # 19 p. 2728 - 2734
反应条件
hydrogenchloride; tetrabutyl ammonium fluoride 1) THF, 0 deg C - rt; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Prakash, G. K. Surya; Krishnamurti, Ramesh; Olah, George A.
Journal of the American Chemical Society, 1989 , vol. 111, # 1 p. 393 - 395
反应条件
1: 96 percent / CsF / 1,2-dimethoxy-ethane / 3 h / 25 °C 2: 92 percent / aq. HCl / tetrahydrofuran / 3 h / 20 °C View Scheme
参考文献
Prakash, G.K. Surya; Tongco, Emily C.; Mathew, Thomas; Vankar, Yashwant D.; Olah, George A.
Journal of Fluorine Chemistry, 2000 , vol. 101, # 2 p. 199 - 202
