1: pyridine; 4-(N,N-dimethlyamino)pyridine / chloroform / 8 h / 0 °C / Inert atmosphere 2: silver tetrafluoroborate / toluene / 8 h / 80 °C / Inert atmosphere; Darkness 3: sodium methylate / methanol / 3 h / 20 °C / Inert atmosphere 4: carbon tetrabromide; tri-n-octyl phosphine / diethyl ether / 4 h / 0 °C / Inert atmosphere 5: CaCl2x2H2O; potassium hydroxide / methanol / 8 h / 0 °C / Inert atmosphere View Scheme

Multi-step reaction with 2 steps 1: pyridine; 4-(N,N-dimethlyamino)pyridine / chloroform / 8 h / 0 °C / Inert atmosphere2: silver tetrafluoroborate / toluene / 8 h / 80 °C / Inert atmosphere; Darkness  

Multi-step reaction with 4 steps 1: pyridine; 4-(N,N-dimethlyamino)pyridine / chloroform / 8 h / 0 °C / Inert atmosphere2: silver tetrafluoroborate / toluene / 8 h / 80 °C / Inert atmosphere; Darkness3: sodium methylate / methanol / 3 h / 20 °C / Inert atmosphere4: carbon tetrabromide; tri-n-octyl phosphine / diethyl ether / 4 h / 0 °C / Inert atmosphere