甲基3-(2-喹啉基甲氧基)苯乙酰氧肟酸盐合成路线 （共 3 条）
反应条件
N'-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine in tetrahydrofuran Ambient temperatureovernight;
参考文献
Musser, John H.; Kreft, Anthony F.; Bender, Reinhold H. W.; Kubrak, Dennis M.; Grimes, David; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 240 - 245
反应条件
1: 97 percent / cesium carbonate, potassium iodide / acetone / 40 h / Heating 2: 94 percent / 1 N NaOH / tetrahydrofuran / 3 h / Heating 3: 29 percent / 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide, Et3N / tetrahydrofuran / Ambient temperature; overnight View Scheme
参考文献
Musser, John H.; Kreft, Anthony F.; Bender, Reinhold H. W.; Kubrak, Dennis M.; Grimes, David; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 240 - 245
反应条件
1: 97 percent / cesium carbonate, potassium iodide / acetone / 40 h / Heating 2: 94 percent / 1 N NaOH / tetrahydrofuran / 3 h / Heating 3: 29 percent / 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide, Et3N / tetrahydrofuran / Ambient temperature; overnight View Scheme
参考文献
Musser, John H.; Kreft, Anthony F.; Bender, Reinhold H. W.; Kubrak, Dennis M.; Grimes, David; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 240 - 245
