2-氨基噻唑-4-甲酸甲酯合成路线 （共 9 条）
反应条件
in methanol Hantzsch Thiazole Synthesis; 2 h; Reflux;
参考文献
Lu, Jin-Yong; Riedrich, Matthias; Wojtas, K.Philip; Arndt, Hans-Dieter
Synthesis (Germany), 2013 , vol. 45, # 10 art. no. SS-2013-T0133-FA, p. 1300 - 1311
反应条件
in methanol T=0°C; 1 h; Cooling with ice;
参考文献
Goodnow,, Robert Alan; Huby, Nicholas J.S.; Kong, Norman; McDermott, Lee Apostle; Moliterni, John Anthony; Zhang, Zhuming
Patent: US2006/63814 A1, 2006 ;
Location in patent: Page/Page column 28 ;
US 20060063814 A1
反应条件
1: With sodium methylate in methanol; water T=0°C; 1 h; 2: With ammonium chloride in methanol; water 3: With sodium hydrogencarbonate in methanol; water pH=9;
参考文献
US2006/41146 A1, ;
Page/Page column 24 ;
US 20060041146 A1
反应条件
sulfuric acid 96 h; Heating;
参考文献
Feliu, Lidia; Ajana, Wadi; Joule, John A.; Lopez-Calahorra, Francisco; Alvarez, Mercedes
Heterocycles, 1997 , vol. 45, # 7 p. 1299 - 1308
反应条件
sulfuric acid 96 h; Heating;
参考文献
Feliu, Lidia; Ajana, Wadi; Joule, John A.; Lopez-Calahorra, Francisco; Alvarez, Mercedes
Heterocycles, 1997 , vol. 45, # 7 p. 1299 - 1308
反应条件
sulfuric acid 96 h; Heating;
参考文献
Feliu, Lidia; Ajana, Wadi; Joule, John A.; Lopez-Calahorra, Francisco; Alvarez, Mercedes
Heterocycles, 1997 , vol. 45, # 7 p. 1299 - 1308
反应条件
sodium hydroxide in tetrahydrofuran T=20°C; 2 h;
参考文献
F. HOFFMANN-LA ROCHE AG; GOODNOW JR., Robert Alan; HAMILTON, Matthew Michael; KOWALCZYK, Agnieszka; SIDDURI, Achyutharao
Patent: WO2013/110578 A1, 2013 ;
Location in patent: Page/Page column 47 ;
反应条件
4-(N,N-dimethlyamino)pyridine in tetrahydrofuran; dichloromethane T=20°C;
参考文献
US2006/63814 A1, ;
Page/Page column 61 ;
US 20060063814 A1
反应条件
ammonia T=110°C; 12 h; steel reaction vessel;
参考文献
Sanghvi, Yogesh S.; Larson, Steven B.; Robins, Roland K.; Revankar, Ganapathi R.; Gupta, Pranab K.; et al
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 623 - 633
