N -甲基- 2 -(三正丁基锡)-的1H -吡咯合成路线 （共 3 条）
反应条件
1: 1-methyl-pyrrole With tert.-butyl lithium in tetrahydrofuran; pentane T=-78 - 20°C; 2 h; 2: tributyltin chloride in tetrahydrofuran; pentane T=-78 - 20°C;
参考文献
WO2005/34878 A2, ;
Page/Page column 34; 35 ;
WO 2005/034878 A2
反应条件
n-butyllithium in tetrahydrofuran
反应条件
tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane
Stille coupling; 5 h; Inert atmosphereReflux;
参考文献
Torun, Lokman; Madras, Bertha K.; Meltzer, Peter C.
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 8 p. 2762 - 2772
