二乙基(3-溴丙基)膦酸酯合成路线 （共 22 条）
反应条件
sodium tetrahydroborate; 2,2'-azo-bisisobutyronitrile; tributyltin chloride in toluene 1 h; Heating;
参考文献
Balczewski, Piotr; Pietrzykowski, Witold M.
Tetrahedron, 1996 , vol. 52, # 43 p. 13681 - 13694
反应条件
sodium tetrahydroborate; tributyltin chloride in toluene 2 h; Ambient temperatureIrradiation;
参考文献
Balczewski, Piotr; Pietrzykowski, Witold M.
Tetrahedron, 1996 , vol. 52, # 43 p. 13681 - 13694
反应条件
1: With sodium hydroxide; hydroxylamine hydrochloride in methanol; water T=40 - 45°C; 3 h; 2: With sodium hydrogencarbonate in water pH=8;
参考文献
Hassan, Jomaa
Patent: US6680308 B1, 2004 ;
Location in patent: Page column 14 ;
反应条件
trimethylsilyl bromide in acetonitrile T=40°C; 0.166667 h; microwave irradiation;
参考文献
Tetrahedron Letters, , vol. 47, # 35 p. 6281 - 6284
反应条件
sodium tetrahydroborate; tributyltin chloride in toluene 2 h; Ambient temperatureIrradiation;
参考文献
Tetrahedron, , vol. 52, # 43 p. 13681 - 13694
参考文献
Andaloussi, Mounir; Lindh, Martin; Bjoerkelid, Christofer; Suresh, Surisetti; Wieckowska, Anna; Iyer, Harini; Karlen, Anders; Larhed, Mats
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5403 - 5407
反应条件
1: bis-diphenylphosphine With n-butyllithium in tetrahydrofuran; hexane
T=0°C; 30 h;
2: 3-Bromopropylphosphonic Acid Diethylester in tetrahydrofuran; hexane
T=-78 - 20°C; 2.33333 h;
参考文献
Baber, Angharad; De Vries, Johannes G.; Orpen, A. Guy; Pringle, Paul G.; Von Der Luehe, Karl
Dalton Transactions, 2006 , # 40 p. 4821 - 4828
反应条件
in tetrahydrofuran
T=5 - 20°C; 15 h;
参考文献
Guerrero, Gilles; Mutin, P. Hubert; Dahan, Francoise; Vioux, Andre
Journal of Organometalic Chemistry, 2002 , vol. 649, # 1 p. 113 - 120
反应条件
1: 81 percent / phosphorus pentachloride / CCl4 / 2 h
2: 50 percent / diethyl ether / 2 h / Heating
View Scheme
参考文献
Hewitt, David G.; Teese, Murray W.
Australian Journal of Chemistry, 1984 , vol. 37, # 1 p. 205 - 210
反应条件
1: 46 percent / dimethylformamide / 5 h / 90 - 95 °C
2: 87 percent / Dowex 50x8 (H+, 50-100 mesh) / ethanol / 120 h / Ambient temperature
3: HCl / 1,2-dichloro-ethane / 1 h / -10 - 0 °C
View Scheme
参考文献
Reist; Bradford III; Ruhland-Fritsch; Sturm; Zaveri; Huffman; Sidwell
Nucleosides and Nucleotides, 1994 , vol. 13, # 1-3 p. 539 - 550
