2-氟-6-(2H-1,2,3-噻唑-2-基)苯甲酸合成路线 (共 1 条)
反应条件
copper(l) iodide; trans-N,N'-dimethylcyclohexane-1,2-diamine; caesium carbonate in 1,4-dioxane; water T=60 - 100°C; 4 h; Inert atmosphere;
参考文献
JANSSEN PHARMACEUTICA NV; LETAVIC, Michael; RUDOLPH, Dale, A.; SAVALL, Brad, M.; SHIREMAN, Brock, T.; SWANSON, Devin
Patent: WO2012/145581 A1, 2012 ;
Location in patent: Page/Page column 50 ;
WO 2012/145581 A1