benzotriazol-1-ol; 1,2-dichloro-ethane; triethylamine in N,N-dimethyl-formamide T=20°C; 15 h;

1: ammonium acetate / methanol / 72 h / 10 - 35 °C 2: sodium ethanolate / ethanol / 15 h / 150 °C 3: trichlorophosphate / 0.5 h / 80 °C 4: potassium carbonate / N,N-dimethyl-formamide / 15 h / 10 - 35 °C 5: triethylamine / ethanol / 25 h / 80 - 100 °C 6: caesium carbonate / dimethyl sulfoxide / 5 h / 100 °C 7: sodium hydroxide; water / ethanol / 1 h / 60 °C 8: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 10 - 35 °C / Cooling View Scheme

1: sodium ethanolate / ethanol / 15 h / 150 °C 2: trichlorophosphate / 0.5 h / 80 °C 3: potassium carbonate / N,N-dimethyl-formamide / 15 h / 10 - 35 °C 4: triethylamine / ethanol / 25 h / 80 - 100 °C 5: caesium carbonate / dimethyl sulfoxide / 5 h / 100 °C 6: sodium hydroxide; water / ethanol / 1 h / 60 °C 7: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 10 - 35 °C / Cooling View Scheme