3-溴-6-甲氧基氰基吡啶合成路线 (共 3 条)
反应条件
triethylamine in acetonitrile T=80°C; 15 h; Inert atmosphere;
参考文献
F. HOFFMANN-LA ROCHE AG; GENENTECH, INC; CHEN, Huifen; CRAWFORD, Terry; MAGNUSON, Steven, R.; NDUBAKU, Chudi; WANG, Lan
Patent: WO2013/113669 A1, 2013 ;
Location in patent: Page/Page column 74 ;
反应条件
silver carbonate in toluene T=20°C; In the dark;
参考文献
WO2009/111337 A1, ;
Page/Page column 175 ;
WO 2009/111337 A1
反应条件
1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 16 h / 40 °C / |Inert atmosphere 2: triethylamine / acetonitrile / 15 h / 80 °C / |Inert atmosphere View Scheme