N-BOC-2-哌啶乙酸乙酯合成路线 （共 5 条）
反应条件
ammonium cerium(IV) nitrate in acetonitrile T=-45°C; 2 h;
参考文献
Narasaka, Koichi; Kohno, Yasushi
Bulletin of the Chemical Society of Japan, 1993 , vol. 66, # 11 p. 3456 - 3463
反应条件
triethylamine in dichloromethane T=0°C; 18 h;
参考文献
Fuerstner, Alois; Kennedy, Jason W.J.
Chemistry - A European Journal, 2006 , vol. 12, # 28 p. 7398 - 7410
反应条件
1: 79 percent / H2 / PtO2 / aq. HCl; ethanol / 20 h / 750.06 Torr 2: 94 percent / NEt3 / CH2Cl2 / 18 h / 0 °C View Scheme
参考文献
Chemistry - A European Journal, , vol. 12, # 28 p. 7398 - 7410
参考文献
PROTEOSTASIS THERAPEUTICS, INC.
Patent: US2012/316193 A1, 2012 ;
Location in patent: Page/Page column 51-52 ;
反应条件
1: 95 percent / LDA / tetrahydrofuran / -78 °C 2: TEA / CH2Cl2 / Ambient temperature 3: 82 percent / DBU / dimethylsulfoxide / 4 h / 120 °C View Scheme
参考文献
Kurihara, Takushi; Matsubara, Yoshitaka; Osaki, Hirotaka; Harusawa, Shinya; Yoneda, Ryuji
Heterocycles, 1990 , vol. 30, # 2 p. 885 - 896
