T=200°C; 0.116667 h;

1: 73 percent / Et3N / acetonitrile / 16.5 h / Heating 2: H2 / 5percent Pd/C / tetrahydrofuran / 1 h / Ambient temperature 3: Et3N / acetone / Ambient temperature 4: 53 percent / 0.12 h / 200 °C View Scheme

1: H2 / 5percent Pd/C / tetrahydrofuran / 1 h / Ambient temperature 2: Et3N / acetone / Ambient temperature 3: 53 percent / 0.12 h / 200 °C View Scheme

1: Et3N / acetone / Ambient temperature 2: 53 percent / 0.12 h / 200 °C View Scheme

sodium hydride 1.) DMF, 70-85 deg C, 1.5 h, 2.) DMF, RT, overnight; Yield given. Multistep reaction. Yields of byproduct given;