反应条件
1: 60 percent / NaHCO3 / H2O / 1.5 h / Ambient temperature
2: 1.) 1-hydroxybenzotriazol hydrate, N,N'-dicyclohexyl-carbodiimide / 1.) THF, 0.5 h, room temp., 2.) THF, room temp., overnight
3: 35 percent / 2N NaOH / tetrahydrofuran; H2O / 3 h / Ambient temperature
View Scheme
参考文献
Makovec; Chiste; Bani; et al.
European Journal of Medicinal Chemistry, 1986 , vol. 21, # 1 p. 9 - 20
