噁唑并[5,4-b]吡啶-2(1h)-酮合成路线 （共 8 条）
反应条件
triethylamine in tetrahydrofuran; dichloromethane
参考文献
Adir et Compagnie
Patent: US5130311 A1, 1992 ;
反应条件
triethylamine in tetrahydrofuran; dichloromethane T=-78°C; 6 h;
参考文献
Flouzat, Christine; Blanchet, Maryline; Guillaumet, Gerald
Tetrahedron Letters, 1992 , vol. 33, # 32 p. 4571 - 4574
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in tetrahydrofuran; dichloromethane T=-78°C; 6 h;
参考文献
Flouzat, Christine; Blanchet, Maryline; Guillaumet, Gerald
Tetrahedron Letters, 1992 , vol. 33, # 32 p. 4571 - 4574
反应条件
durch Destillation unter vermindertem Druck;
参考文献
Koshiro
Chemical and Pharmaceutical Bulletin, 1959 , vol. 7, p. 725,729
参考文献
Flouzat, Christine; Blanchet, Maryline; Guillaumet, Gerald
Tetrahedron Letters, 1992 , vol. 33, # 32 p. 4571 - 4574
反应条件
sodium hydride 1.) DMF, 40-50 deg C, 40 min, 2.) DMF, 110 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Viaud, Marie-Claude; Jamoneau, Patricia; Flouzat, Christine; Bizot-Espiard, Jean-Guy; Pfeiffer, Bruno; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 8 p. 1278 - 1286
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene 1.) DMF, 40-50 deg C, 40 min, 2.) DMF, 110 deg C, 3 h; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 33, # 32 p. 4571 - 4574
反应条件
sodium hydride 1.) DMF, 40-50 deg C, 40 min, 2.) DMF, 110 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Viaud, Marie-Claude; Jamoneau, Patricia; Flouzat, Christine; Bizot-Espiard, Jean-Guy; Pfeiffer, Bruno; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 8 p. 1278 - 1286
