N,N-二甲基甲酰胺二乙基缩醛合成路线 （共 152 条）
反应条件
in ethanol 1.5 h; Ambient temperature;
参考文献
Kadushkin, A. V.; Golovko, T. V.; Kalistratov, S. G.; Sokolov, A. S.; Chernov, V. A.; Granik, V. G.
Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 5 p. 317 - 322
Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 5 p. 545 - 550
反应条件
in tetrahydrofuran T=55°C; 3 h;
参考文献
Journal of Physical Organic Chemistry, , vol. 9, # 4 p. 212 - 220
反应条件
T=85°C; 3 h; Yield given. Yields of byproduct given;
参考文献
Dozorova, E. N.; Grizik, S. I.; Granik, V. G.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1990 , vol. 26, # 1 p. 70 - 73
Khimiya Geterotsiklicheskikh Soedinenii, 1990 , # 1 p. 81 - 84
参考文献
IRM LLC
Patent: US2012/65184 A1, 2012 ;
Location in patent: Page/Page column 37 ;
US 20120065184 A1
反应条件
in xylene T=130°C; 48 h; Heating / reflux;
参考文献
NIPPON KAYAKU KABUSHIKI KAISHA
Patent: EP1674454 A1, 2006 ;
Location in patent: Page/Page column 19 ;
反应条件
1: in N,N-dimethyl-formamide 1 h; Heating; 2: With ammonium chloride in ethanol 0.5 h; Heating; Further stages.;
参考文献
Delfourne, Evelyne; Darro, Francis; Portefaix, Philippe; Galaup, Chantal; Bayssade, Sylvie; Bouteille, Anne; Le Corre, Laurent; Bastide, Jean; Collignon, Francoise; Lesur, Brigitte; Frydman, Armand; Kiss, Robert
Journal of Medicinal Chemistry, 2002 , vol. 45, # 17 p. 3765 - 3771
反应条件
in ethanol T=20°C; 3 h; Yield given. Yields of byproduct given;
参考文献
Golovko, T. V.; Solov'eva, N. P.; Bogdanova, G. A.; Sheinker, Yu. N.; Granik, V. G.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1991 , vol. 27, # 9 p. 952 - 959
Khimiya Geterotsiklicheskikh Soedinenii, 1991 , # 9 p. 1190 - 1198
参考文献
Meerwein,H. et al.
Justus Liebigs Annalen der Chemie, 1961 , vol. 641, p. 1 - 39
反应条件
1: 5-amino-4-(cyanoformimidoyl)-1H-imidazole; dimethyl amine in chloroform T=20°C; 5 h; 2: 1,1-diethoxy-N,N-dimethylmethanamine in chloroform T=20°C; 7 h; Further stages.;
参考文献
Alves, M. Jose; Carvalho, M. Alice; Carvalho, Silvia; Dias, Alice M.; Fernandes, Francisco H.; Proenca, M. Fernanda
European Journal of Organic Chemistry, 2007 , # 29 p. 4881 - 4887
参考文献
Osek, Jerzy; Oszczapowicz, Janusz; Drzewinski, Witold
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1986 , p. 1961 - 1964
