(S)-2-氨甲基-1-Cbz-吡咯烷合成路线 (共 8 条)
反应条件
water; ammonium chloride; zinc in ethanol T=20°C;
参考文献
Bagdziunas, Gintautas; Haukka, Matti; Butkus, Eugenijus
Synthetic Communications, 2011 , vol. 41, # 17 p. 2517 - 2523
反应条件
1: With borane in tetrahydrofuran 7 h; Heating; 2: With hydrogenchloride 6 h; Heating; Further stages.;
参考文献
SCIENCE and TECHNOLOGY CORPORATION &at; UNM
Patent: WO2006/7586 A1, 2006 ;
Location in patent: Page/Page column 31-32 ;
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=-10°C;
参考文献
Journal of Organic Chemistry, , vol. 74, # 15 p. 5260 - 5266
反应条件
1: pyridine / 0 deg C to room temperature 2: NaN3 / dimethylformamide / Heating 3: PPh3, aq. NH3 / methanol View Scheme
参考文献
Tetrahedron Letters, , vol. 32, # 49 p. 7183 - 7186
反应条件
1: BH3 / tetrahydrofuran / 0 deg C to room temperature 2: pyridine / 0 deg C to room temperature 3: NaN3 / dimethylformamide / Heating 4: PPh3, aq. NH3 / methanol View Scheme
参考文献
Tetrahedron Letters, , vol. 32, # 49 p. 7183 - 7186
反应条件
1: NaN3 / dimethylformamide / Heating 2: PPh3, aq. NH3 / methanol View Scheme
参考文献
Tetrahedron Letters, , vol. 32, # 49 p. 7183 - 7186
反应条件
1: aq. Na2CO3 2: BH3 / tetrahydrofuran / 0 deg C to room temperature 3: pyridine / 0 deg C to room temperature 4: NaN3 / dimethylformamide / Heating 5: PPh3, aq. NH3 / methanol View Scheme
参考文献
Tetrahedron Letters, , vol. 32, # 49 p. 7183 - 7186
反应条件
1: aq. Na2CO3 2: BH3 / tetrahydrofuran / 0 deg C to room temperature 3: pyridine / 0 deg C to room temperature 4: NaN3 / dimethylformamide / Heating 5: PPh3, aq. NH3 / methanol View Scheme
参考文献
Tetrahedron Letters, , vol. 32, # 49 p. 7183 - 7186