1: lithium aluminium hydride / tetrahydrofuran / 4 h / Heating 2: pyridine / 24 h / 25 °C View Scheme

1: 90.9 percent / LiAlH4 / diethyl ether / 15 h 2: 81.63 percent / pyridinium chlorochromate (PCC), AcONa / CH2Cl2 / 4 h View Scheme

lithium aluminium tetrahydride in diethyl ether 15 h;

<b>Multi-step reaction with 2 steps<br /> </b>1: 70 percent / PCC, NaOAc / CH₂Cl₂ / 24 h / Ambient temperature<br />2: n-BuLi / toluene / 2 h / 25 &deg;C<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11342937', constants.ctx, '0')">potassium hydroxide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1098229', constants.ctx, '0')">methanol</a> <br />&nbsp;electrosynthesis;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 90 percent / H₂SO₄ / 24 h / Heating<br />2: 70 percent / PCC, NaOAc / CH₂Cl₂ / 24 h / Ambient temperature<br />3: n-BuLi / toluene / 2 h / 25 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 92 percent / 2N NaOH / 5 h / Heating<br />2: 90 percent / H₂SO₄ / 24 h / Heating<br />3: 70 percent / PCC, NaOAc / CH₂Cl₂ / 24 h / Ambient temperature<br />4: n-BuLi / toluene / 2 h / 25 &deg;C<br /> <br /> &nbsp;