2-(1H-2-咪唑基)吡嗪合成路线 (共 1 条)
反应条件
1: 2,2-diethoxy-ethanamine With sodium methylate in methanol T=20°C; 0.416667 h; 2: pyrazinecarbonitrile With acetic acid T=50°C; 1 h; 3: With hydrogenchloride in methanol Reflux;
参考文献
WO2012/93148 A1, ;
Page/Page column 36-37 ;
WO 2012/093148 A1