1-(4-羟基苄基)-1,2,4-噻唑合成路线 （共 4 条）
反应条件
hydrogen; 10 palladium on activated carbon in tetrahydrofuran; ethanol T=20°C; 72 h;
参考文献
Potter, Barry Victor Lloyd; Woo, Lok Wai Lawrence; Purohit, Atul; Reed, Michael John; Sutcliffe, Oliver Brook; Bubert, Christian
Patent: US2004/19016 A1, 2004 ;
Location in patent: Page/Page column 82 ;
反应条件
sodium nitrate; sulfuric acid in water room temp., 20 min, 85 deg C, 35 min;
参考文献
Andreini; Biagi; Giorgi; Livi; Scartoni
Farmaco, 1989 , vol. 44, # 9 p. 831 - 841
反应条件
1: 71 percent / sodium ethoxide / ethanol / room temp. 4 h, reflux, 1 h 2: 96 percent / hydrogen / 5percent Pd/C / ethanol / Ambient temperature 3: 88 percent / H2SO4, NaNO3 / H2O / room temp., 20 min, 85 deg C, 35 min View Scheme
参考文献
Andreini; Biagi; Giorgi; Livi; Scartoni
Farmaco, 1989 , vol. 44, # 9 p. 831 - 841
反应条件
1: 96 percent / hydrogen / 5percent Pd/C / ethanol / Ambient temperature 2: 88 percent / H2SO4, NaNO3 / H2O / room temp., 20 min, 85 deg C, 35 min View Scheme
参考文献
Andreini; Biagi; Giorgi; Livi; Scartoni
Farmaco, 1989 , vol. 44, # 9 p. 831 - 841
