3-氨基四氢呋喃-2-酮氢溴酸盐合成路线 （共 21 条）
反应条件
sodium hydride 2) DMF, 40 - 50 deg C; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Krief, A.; Trabelsi, M.
Synthetic Communications, 1989 , vol. 19, # 7,8 p. 1203 - 1210
反应条件
sodium hydride 2) DMF, 40 - 50 deg C; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Krief, A.; Trabelsi, M.
Synthetic Communications, 1989 , vol. 19, # 7,8 p. 1203 - 1210
反应条件
1: 2ABL in 1-methyl-pyrrolidin-2-one T=20°C; 0.166667 h; 2: lithium methaneselenolate in tetrahydrofuran; 1-methyl-pyrrolidin-2-one T=60°C; 1 h;
参考文献
US2013/184474 A1, ;
Paragraph 0042; 0043; 0044; 0046 ;
反应条件
in 1-methyl-pyrrolidin-2-one T=20 - 150°C; 1.16667 h;
参考文献
US2013/184474 A1, ;
Paragraph 0025; 0028 ;
反应条件
in 1-methyl-pyrrolidin-2-one T=20 - 150°C; 1.16667 h;
参考文献
US2013/184474 A1, ;
Paragraph 0025; 0028 ;
反应条件
1: 2ABL in 1-methyl-pyrrolidin-2-one T=20°C; 0.166667 h; 2: sodium methylselenolate in 1-methyl-pyrrolidin-2-one T=90°C; 1 h;
参考文献
ADISSEO FRANCE S.A.S.; Huet, Robert; Joerger, Jean-Michel; Henryon, Vivien
Patent: US2013/184474 A1, 2013 ;
Location in patent: Paragraph 0038; 0039; 0041 ;
反应条件
1: 2ABL in 1-methyl-pyrrolidin-2-one T=20°C; 0.166667 h; 2: lithium methaneselenolate in tetrahydrofuran; 1-methyl-pyrrolidin-2-one T=60°C; 1 h;
参考文献
US2013/184474 A1, ;
Paragraph 0042; 0043; 0044; 0046 ;
反应条件
sodium hydride 2) DMF, 40 - 50 deg C; Yield given. Multistep reaction;
参考文献
Krief, A.; Trabelsi, M.
Synthetic Communications, 1989 , vol. 19, # 7,8 p. 1203 - 1210
反应条件
sodium hydride 2) DMF, 40 - 50 deg C; Yield given. Multistep reaction;
参考文献
Krief, A.; Trabelsi, M.
Synthetic Communications, 1989 , vol. 19, # 7,8 p. 1203 - 1210
参考文献
Knoll A.G.
Patent: DE816544 , 1950 ;
DRP/DRBP Org.Chem.
