反应条件
1: 95 percent / Zn dust / diethyl ether / 3 h / 20 °C / ultrasonic bath
2: 88.9 percent / Zn dust, acetic acid / H2O / Ambient temperature
3: 1.) LDA / 1.) hexane, Et2O, THF, -78 deg C, 10 min; 2.) hexane, Et2O, THF, RT, 2 h
4: 84.9 percent / 20 percent NaOH / methanol; tetrahydrofuran / 2 h / Heating
5: 91 percent / diethyl ether / 2 h / 0 °C
6: 96 percent / 85 percent phosphoric acid, 88 percent formic acid / 3 h / 85 - 90 °C
View Scheme
参考文献
Gruhn; Reusch
Tetrahedron, 1993 , vol. 49, # 36 p. 8159 - 8168
