2,5-二氯-4-甲基嘧啶合成路线 （共 2 条）
反应条件
iron (III) acetylacetonate in tetrahydrofuran; NMP (N-methylpyrrolidone); diethyl ether T=0°C; 0.5 h;
参考文献
JANSSEN PHARMACEUTICA NV; BRANSTETTER, Bryan, James; LETAVIC, Michael, A.; LY, Kiev, S.; RUDOLPH, Dale, A.; SAVALL, Brad, M.; SHAH, Chandravadan, R.; SHIREMAN, Brock, T.
Patent: WO2011/50202 A1, 2011 ;
Location in patent: Page/Page column 57 ;
WO 2011/050202 A1
反应条件
iron (III) acetylacetonate in tetrahydrofuran; 1-methyl-pyrrolidin-2-one T=20°C; Inert atmosphere;
参考文献
WO2009/129036 A1, ;
Page/Page column 80-81 ;
WO 2009/129036 A1
