3-(4-联苯基)-2-({[(2-甲基-2-丙基)氧基]羰基}氨基)丙酸合成路线 （共 5 条）
反应条件
dipotassium hydrogenphosphate; formic acid; Pd(OAc)2(2-amino-4,6-dihydroxypyrimidine disodium salt)2 in water T=37°C; Suzuki-Miyaura coupling; 4 h;
参考文献
Chalker, Justin M.; Wood, Charlotte S. C.; Davis, Benjamin G.
Journal of the American Chemical Society, 2009 , vol. 131, # 45 p. 16346 - 16347
反应条件
dipotassium hydrogenphosphate; formic acid; Pd(OAc)2(2-amino-4,6-dihydroxypyrimidine disodium salt)2 in water T=37°C; Suzuki-Miyaura coupling; 4 h;
参考文献
Chalker, Justin M.; Wood, Charlotte S. C.; Davis, Benjamin G.
Journal of the American Chemical Society, 2009 , vol. 131, # 45 p. 16346 - 16347
反应条件
sodium hydroxide in tetrahydrofuran; methanol Ambient temperature;
参考文献
Ksander, Gary M.; Ghai, Raj D.; deJesus, Reynalda; Diefenbacher, Clive G.; Yuan, Andrew; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 10 p. 1689 - 1700
反应条件
trifluoroacetic acid in dichloromethane T=25°C; 2 h;
参考文献
Prior, Allan M.; Kim, Yunjeong; Weerasekara, Sahani; Moroze, Meghan; Alliston, Kevin R.; Uy, Roxanne Adeline Z.; Groutas, William C.; Chang, Kyeong-Ok; Hua, Duy H.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 23 p. 6317 - 6320
反应条件
thionyl chloride
T=0 - 20°C;
参考文献
Mollica, Adriano; Feliciani, Federica; Stefanucci, Azzurra; Costante, Roberto; Lucente, Gino; Pinnen, Francesco; Notaristefano, Daniela; Spisani, Susanna
Journal of Peptide Science, 2012 , vol. 18, # 6 p. 418 - 426
