N-(3,5-二氟苯基)-2-吡啶硫代甲酰胺合成路线 (共 4 条)
反应条件
in dichloromethane; toluene; Petroleum ether
参考文献
American Home Products Corporation
Patent: US4886821 A1, 1989 ;
反应条件
Lawesson's reagent in toluene 4 h; Heating;
参考文献
Kinney, William A.; Lee, Nancy E.; Blank, Robert M.; Demerson, Christopher A.; Sarnella, Carol S.; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 327 - 336
反应条件
1: 1.) 1,1'-carbonyldiimidazole / 1.) DMF, 1 h, 2.) 3 d 2: 58 percent / Lawesson's reagent / toluene / 4 h / Heating View Scheme
参考文献
Kinney, William A.; Lee, Nancy E.; Blank, Robert M.; Demerson, Christopher A.; Sarnella, Carol S.; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 327 - 336
反应条件
1: 1.) 1,1'-carbonyldiimidazole / 1.) DMF, 1 h, 2.) 3 d 2: 58 percent / Lawesson's reagent / toluene / 4 h / Heating View Scheme
参考文献
Kinney, William A.; Lee, Nancy E.; Blank, Robert M.; Demerson, Christopher A.; Sarnella, Carol S.; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 327 - 336