1: 2-hydroxy-benzopyrazine With sodium hydride in N,N-dimethyl-formamide; mineral oil 0.25 h; 2: 4,6-dichloro-pyrimidine in N,N-dimethyl-formamide; mineral oil T=20°C;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: US2012/88755 A1, 2012 ;
Location in patent: Page/Page column 61 ;