4,6-二氯嘧啶合成路线

4,6-二氯嘧啶合成路线（共 112 条）

参考文献

WO2011/63272 A1, ;

Page/Page column 46 ;
WO 2011/063272 A1

1193-21-14,6-二氯嘧啶

2802-62-24,6-二氟嘧啶

参考文献

American Cyanamid Company
Patent: EP794177 A1, 1997 ;

1193-21-14,6-二氯嘧啶

2802-62-24,6-二氟嘧啶

参考文献

Imperial Chemical Industries PLC
Patent: US5145856 A1, 1992 ;

1193-21-14,6-二氯嘧啶+

75-04-7乙胺

872511-30-34-氯-6-乙基氨基嘧啶

参考文献

Guagnano, Vito; Furet, Pascal; Spanka, Carsten; Bordas, Vincent; Le Douget, Mickael; Stamm, Christelle; Brueggen, Josef; Jensen, Michael R.; Schnell, Christian; Schmid, Herbert; Wartmann, Markus; Berghausen, Joerg; Drueckes, Peter; Zimmerlin, Alfred; Bussiere, Dirksen; Murray, Jeremy; Graus Porta, Diana
Journal of Medicinal Chemistry, 2011 , vol. 54, # 20 p. 7066 - 7083

1193-21-14,6-二氯嘧啶

289-95-2嘧啶

参考文献

Smith; Christensen
Journal of Organic Chemistry, 1955 , vol. 20, p. 829,833,835

1193-21-14,6-二氯嘧啶+

714962-04-6+

461-82-5对三氟甲氧基苯胺

778270-11-43-[6-[[4-(三氟甲氧基)苯基]氨基]-4-嘧啶基]苯甲酰胺

参考文献

IRM LLC
Patent: US2011/21524 A1, 2011 ;

1193-21-14,6-二氯嘧啶+

74-89-5甲胺

933702-18-2

参考文献

NOVARTIS AG; BERGHAUSEN, Joerg; KAPA, Prasad, Koteswara; MCKENNA, Joseph; SLADE, Joel; WU, Raeann; DU, Zhengming
Patent: WO2011/71821 A1, 2011 ;
Location in patent: Page/Page column 22 ;
WO 2011/071821 A1

1193-21-14,6-二氯嘧啶

2434-56-24,6-二氨基嘧啶

参考文献

Kenner et al.
Journal of the Chemical Society, 1943 , p. 574

1193-21-14,6-二氯嘧啶+

67-63-0异丙醇

83774-13-44-氯-6-异丙氧基-嘧啶

参考文献

Lee, Hong Woo; Bok, Young Kim; Joong, Bok Ahn; Sung, Kwon Kang; Lee, Jung Hwa; Jae, Soo Shin; Soon, Kil Ahn; Lee, Sang Joon; Seung, Soo Yoon
European Journal of Medicinal Chemistry, 2005 , vol. 40, # 9 p. 862 - 874

1193-21-14,6-二氯嘧啶

83774-13-44-氯-6-异丙氧基-嘧啶

参考文献

Pfizer Inc.
Patent: US4435401 A1, 1984 ;

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