2-甲基-1,3-环己二酮合成路线 （共 134 条）
反应条件
pyridinium p-toluenesulfonate in neat (no solvent)
T=200°C; 0.25 h;
参考文献
Coates, Robert M.; Hobbs, Steven J.
Journal of Organic Chemistry, 1984 , vol. 49, p. 140 - 152
反应条件
1: 100 percent / pyridine / CH2Cl2 / -78 - 0 °C
2: 63 percent / diethyl ether; toluene / 1.33 h / -78 - 60 °C
View Scheme
参考文献
Batsomboon, Paratchata; Gold, Brian A.; Alabugin, Igor V.; Dudley, Gregory B.
Synthesis (Germany), 2012 , vol. 44, # 12 art. no. SS-2012-C0221-ST, p. 1818 - 1824
反应条件
N-benzyl-trimethylammonium hydroxide in benzene
Ambient temperature;
参考文献
Ramadas, S. R.; Chenchaiah, P. Ch.; Rao, J. Appa; Kumareasan, S.
Tetrahedron Letters, 1983 , vol. 24, # 48 p. 5403 - 5406
反应条件
1: 75 percent / Triton B / benzene / Ambient temperature
2: lithium tritertiarybutoxyaluminium hydride
View Scheme
参考文献
Ramadas, S. R.; Chenchaiah, P. Ch.; Rao, J. Appa; Kumareasan, S.
Tetrahedron Letters, 1983 , vol. 24, # 48 p. 5403 - 5406
反应条件
1: 85 percent / 1M aq. NaOH / 24 h
2: 98 percent / H2 / PtO2 / ethanol / 4 h
View Scheme
参考文献
Brooks, Dee W.; Mazdiyasni, Hormoz; Chakrabarti, Sharmistha
Tetrahedron Letters, 1984 , vol. 25, # 12 p. 1241 - 1244
反应条件
tetrabutyl ammonium fluoride
2.) 25 deg C, 64 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Brooks, Dee W.; Mazdiyasni, Hormoz; Chakrabarti, Sharmistha
Tetrahedron Letters, 1984 , vol. 25, # 12 p. 1241 - 1244
反应条件
1.1: 100 percent / pyridine / CH2Cl2 / -78 - 0 °C
2.1: LiHMDS / tetrahydrofuran / 0.5 h / -78 °C
2.2: 21 percent / tetrahydrofuran / -78 - 60 °C
View Scheme
参考文献
Lisboa, Marilda P.; Jones, David M.; Dudley, Gregory B.
Organic Letters, 2013 , vol. 15, # 4 p. 886 - 889
反应条件
hydroquinone in water
T=70 - 80°C; 4 h;
参考文献
Harada, Nobuyuki; Sugioka, Tatsuo; Uda, Hisashi; Kuriki, Takeo
Synthesis, 1990 , p. 53 - 56
反应条件
magnesium oxide
T=100°C; Robinson annelation; P=75007.5 Torr; 2 h;
参考文献
Kawanami, Hajime; Ikushima, Yutaka
Tetrahedron Letters, 2004 , vol. 45, # 26 p. 5147 - 5150
反应条件
1: (i) NaOMe, MeOH, dioxane, (ii) /BRN= 635772/
2: H2 / Pd-BaSO4 / acetone
View Scheme
参考文献
Kochetkov,N.K.; Gottikh,B.P.
J. Gen. Chem. USSR (Engl. Transl.), 1960 , vol. 30, p. 948 - 953,963 - 968
