2-甲基-1,3-环己二酮合成路线 （共 134 条）
反应条件
bis(.eta.5-cyclopentadienyl)hafnium dihydride in isopropyl alcohol T=80°C; 8 h;
参考文献
Journal of Organic Chemistry, , vol. 53, # 16 p. 3752 - 3757
反应条件
1: 93 percent / p-toluenesulfonic acid monohydrate / benzene / 36 h / Heating 2: 1.) LDA / 1.) hexane, THF, -78 deg C, 45 min, 2.) hexane, THF, from -78 deg C to RT, 12 h 3: 1.) Mg, 3.) aq. HCl 4: 1.) t-BuOH, Li, NH3(liquid), 3.) 4percent KOH View Scheme
参考文献
Paquette, Leo A.; Sauer, Daryl R.; Cleary, Darryl G.; Kinsella, Mary A.; Blackwell, Christopher M.; Anderson, Lawrence G.
Journal of the American Chemical Society, 1992 , vol. 114, # 19 p. 7375 - 7387
反应条件
1: 2-methylcyclohexanone-1,3-dione; methyl iodide With potassium carbonate in acetone Heating; 2: ethylene glycol With camphor-10-sulfonic acid; orthoformic acid triethyl ester in dichloromethane Further stages.;
参考文献
Pettersson, Martin; Knueppel, Daniel; Martin, Stephen F.
Organic Letters, 2007 , vol. 9, # 22 p. 4623 - 4626
反应条件
1: p-TsOH / benzene / 12 h / Heating 2: 4.83 g / tetrahydrofuran / 15 h / 0 °C 3: 97 percent / diisobutylaluminium hydride / hexane; CH2Cl2 / 0.17 h / 0 °C View Scheme
参考文献
Kita; Furukawa; Futamura; Ueda; Sawama; Hamamoto; Fujioka
Journal of Organic Chemistry, 2001 , vol. 66, # 26 p. 8779 - 8786
反应条件
oxygen; Manganese (II) acetate in acetic acid T=23°C; 12 h;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 65, # 5 p. 1371 - 1378
反应条件
1: H2 / Raney-Ni / ethanol / 100 °C / 76000 Torr 2: 72 percent / pyridine / Ambient temperature 3: 40 percent / <Pr4N>Br / dimethylformamide / electrochemical reduction (Pt-electrode) View Scheme
参考文献
Hoffmann, Joachim; Holst, Hartmut; Volz, Wolfgang; Voss, Juergen
Journal of Chemical Research, Miniprint, 1989 , # 2 p. 401 - 428
反应条件
sea sand; sodium ethanolate; potassium hexacyanoferrate(III) 1.) RT, 10 min, 2.) RT, 3 h; Yield given. Multistep reaction;
参考文献
Kornblum, Nathan; Kelly, William J.; Kestner, M. M.
Journal of Organic Chemistry, 1985 , vol. 50, # 24 p. 4720 - 4724
反应条件
oxygen; Manganese (II) acetate in acetic acid T=23°C; 12 h;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 65, # 5 p. 1371 - 1378
反应条件
magnesium oxide T=100°C; Robinson annelation; P=75007.5 Torr; 2 h;
参考文献
Kawanami, Hajime; Ikushima, Yutaka
Tetrahedron Letters, 2004 , vol. 45, # 26 p. 5147 - 5150
反应条件
1: With aluminum oxide T=20°C; Michael addition; 0.166667 h; 2: With pyrrolidine Robinson annulation; 0.05 h; microwave irradiation;
参考文献
Chemical and pharmaceutical bulletin, , vol. 51, # 4 p. 455 - 457
