2-甲基-1,3-环己二酮合成路线 （共 134 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene; lithium bromide in tetrahydrofuran 1.) 30 min, r.t.; 2.) 11 h, ref.;
参考文献
Bedekar; Watanabe; Tanaka; Fuji
Synthesis, 1995 , # 9 p. 1069 - 1070
反应条件
potassium carbonate in acetone Reflux;
参考文献
Basu, Debjit; Chandrasekharam, Malapaka; Mainkar, Prathama S; Chandrasekhar, Srivari
Arkivoc, 2011 , vol. 2011, # 2 p. 355 - 362
反应条件
1: NaOAll 2: 190 - 200 °C View Scheme
参考文献
Tamura,Y. et al.
Chemical and Pharmaceutical Bulletin, 1971 , vol. 19, p. 571 - 575
反应条件
1: 40 percent / 40percent methanolic Triton-B, tert-butanol / xylene / 6 h / Heating 2: 35 percent / p-toluenesulfonic acid / benzene / 10 h / Ambient temperature View Scheme
参考文献
Babu; Ramana; Ramadas
Steroids, 1991 , vol. 56, # 7 p. 388 - 391
反应条件
pyridine in dichloromethane T=-78 - 0°C;
参考文献
Jones, David M.; Dudley, Gregory B.
Synlett, 2010 , # 2 p. 223 - 226
反应条件
1: 2-methylcyclohexanone-1,3-dione With N,N'-dimethyl-N,N'-propyleneurea; lithium diisopropyl amide in tetrahydrofuran T=-78°C; 2 h; 2: N-phenyl-1,1,1-trifluoromethanesulfonamide in tetrahydrofuran T=0°C; 9 h;
参考文献
Scheiper, Bodo; Bonnekessel, Melanie; Krause, Helga; Fuerstner, Alois
Journal of Organic Chemistry, 2004 , vol. 69, # 11 p. 3943 - 3949
反应条件
sodium hydride in tetrahydrofuran; N,N-dimethyl-formamide 1.) 0 deg C, 30 min, 2.) r.t., 30 min;
参考文献
Yamano, Yumiko; Mimuro, Mamoru; Ito, Masayoshi
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 18 p. 2713 - 2724
反应条件
toluene-4-sulfonic acid in toluene
Heating / reflux;
参考文献
MEIJI DAIRIES CORPORATION
Patent: WO2004/87630 A1, 2004 ;
Location in patent: Page 7-8 ;
反应条件
sodium hydride
1.) THF, 2.) destill., 0.013kPa; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Garst, Michael E.; McBride, Bill J.
Journal of Organic Chemistry, 1983 , vol. 48, # 8 p. 1362 - 1364
参考文献
Crispin; Vanstone; Whithurst
Journal of the Chemical Society. Perkin transactions 1, 1970 , vol. 1, p. 10 - 18
