2-甲基-1,3-环己二酮合成路线 （共 134 条）
反应条件
sodium hydride
1.) THF, 2.) C8H10, 24 h, reflux; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Garst, Michael E.; McBride, Bill J.
Journal of Organic Chemistry, 1983 , vol. 48, # 8 p. 1362 - 1364
反应条件
ethanol; sulfuric acid
参考文献
Meek et al.
Journal of the Chemical Society, 1953 , p. 811,813
反应条件
toluene-4-sulfonic acid in benzene
6 h; Heating;
参考文献
Paquette, Leo A.; Sauer, Daryl R.; Cleary, Darryl G.; Kinsella, Mary A.; Blackwell, Christopher M.; Anderson, Lawrence G.
Journal of the American Chemical Society, 1992 , vol. 114, # 19 p. 7375 - 7387
反应条件
1: diethyl ether
2: LiAlH4
View Scheme
参考文献
Born et al.
Journal of the Chemical Society, 1953 , p. 1779,1781
反应条件
palladium diacetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine in tetrahydrofuran
16 h; Heating;
参考文献
Schuda, Paul Francis; Bernstein, Barnett
Synthetic Communications, 1984 , vol. 14, # 4 p. 293 - 300
反应条件
potassium hydroxide; potassium iodide
参考文献
Kobayashi,M.; Matsumoto,T.
Bulletin of the Chemical Society of Japan, 1979 , vol. 52, p. 2978 - 2990
反应条件
1: 93 percent / p-toluenesulfonic acid monohydrate / benzene / 36 h / Heating
2: 1.) LDA / 1.) hexane, THF, -78 deg C, 45 min, 2.) hexane, THF, from -78 deg C to RT, 12 h
View Scheme
参考文献
Paquette, Leo A.; Sauer, Daryl R.; Cleary, Darryl G.; Kinsella, Mary A.; Blackwell, Christopher M.; Anderson, Lawrence G.
Journal of the American Chemical Society, 1992 , vol. 114, # 19 p. 7375 - 7387
反应条件
potassium methanolate in methanol; diethyl ether; dimethyl sulfoxide
8 h; Heating;
参考文献
Subbaraj,A. et al.
Synthetic Communications, 1977 , vol. 7, p. 433 - 439
反应条件
1: 85 percent / t-BuOK / 2-methyl-propan-2-ol / 96 h / 60 °C
2: 72 percent / Saccharomyces cerevisiae
View Scheme
参考文献
Laverde Jr., Antonio; Da Conceicao, Gelson J. A.; Queiroz, Sonia C. N.; Fujiwara, Fred Y.; Marsaioli, Anita J.
Magnetic Resonance in Chemistry, 2002 , vol. 40, # 7 p. 433 - 442
反应条件
in neat (no solvent)
T=200°C; 2 h;
参考文献
Coates, Robert M.; Hobbs, Steven J.
Journal of Organic Chemistry, 1984 , vol. 49, p. 140 - 152
