反应条件
1: pyrrole; 2,2,2-trichloroacetyl chloride With 4-methyl-morpholine in tert-butyl methyl ether T=10 - 30°C; Friedel Crafts acylation; Large scale reaction; 2: sodium methylate in methanol; tert-butyl methyl ether T=20 - 35°C; Large scale reaction;
参考文献
Tudge, Matthew; Savarin, Cecile G.; Difelice, Katherine; Maligres, Peter; Humphrey, Guy; Reamer, Bob; Tellers, David M.; Hughes, Dave
Organic Process Research and Development, 2010 , vol. 14, # 4 p. 787 - 798
