2-(4-吗啉基)-16-(1-吡咯基)-雄甾-3,17-二醇合成路线 （共 13 条）
反应条件
toluene-4-sulfonic acid in water T=20 - 110°C; 40 h; Heating / reflux; Product distribution / selectivity;
参考文献
Mendez, Juana Araceli; De La Mora, Marco A.; Rodriguez, Angel A.; Barragan, Efrain; Herrera, Hugo; Guillen, Alejandro
Patent: US2007/117975 A1, 2007 ;
Location in patent: Page/Page column 12 ;
反应条件
hydrogenchloride in water T=20 - 110°C; 40 h; Heating / reflux; Product distribution / selectivity;
参考文献
US2007/117975 A1, ;
Page/Page column 13 ;
反应条件
sulfuric acid in water T=20 - 110°C; 40 h; Heating / reflux; Product distribution / selectivity;
参考文献
US2007/117975 A1, ;
Page/Page column 13 ;
反应条件
anhydrous iron chloride in water T=20 - 110°C; 40 h; Heating / reflux; Product distribution / selectivity;
参考文献
US2007/117975 A1, ;
Page/Page column 14 ;
反应条件
zinc diacetate in water T=20 - 110°C; 40 h; Heating / reflux; Product distribution / selectivity;
参考文献
US2007/117975 A1, ;
Page/Page column 13 ;
反应条件
in water T=20 - 110°C; 40 h; Heating / reflux; Product distribution / selectivity;
参考文献
US2007/117975 A1, ;
Page/Page column 14 ;
反应条件
in dichloromethane; water T=20 - 22°C; 22 h; Product distribution / selectivity;
参考文献
Mendez, Juana Araceli; De La Mora, Marco A.; Rodriguez, Angel A.; Barragan, Efrain; Herrera, Hugo; Guillen, Alejandro
Patent: US2007/117975 A1, 2007 ;
Location in patent: Page/Page column 16 ;
反应条件
triethylamine in dichloromethane T=20 - 22°C; 22 h; Product distribution / selectivity;
参考文献
Mendez, Juana Araceli; De La Mora, Marco A.; Rodriguez, Angel A.; Barragan, Efrain; Herrera, Hugo; Guillen, Alejandro
Patent: US2007/117975 A1, 2007 ;
Location in patent: Page/Page column 15 ;
反应条件
in dichloromethane T=25°C; 48 h; Product distribution / selectivity;
参考文献
GLAND PHARMA LIMITED
Patent: WO2009/16648 A2, 2009 ;
Location in patent: Page/Page column 8-9 ;
反应条件
in dichloromethane T=0 - 40°C; 18 h; Product distribution / selectivity;
参考文献
US2005/159398 A1, ;
Page/Page column 8 ;
