(2b,3a,5a,16b,17b)-17-乙酰氧基-3-羟基-2-(4-吗啉基)-16-(1-吡咯烷基)雄甾烷合成路线 (共 6 条)
反应条件
triethylamine in dichloromethane T=20 - 22°C; 22 h; Product distribution / selectivity;
参考文献
Mendez, Juana Araceli; De La Mora, Marco A.; Rodriguez, Angel A.; Barragan, Efrain; Herrera, Hugo; Guillen, Alejandro
Patent: US2007/117975 A1, 2007 ;
Location in patent: Page/Page column 15 ;
反应条件
in dichloromethane T=25°C; 48 h; Product distribution / selectivity;
参考文献
GLAND PHARMA LIMITED
Patent: WO2009/16648 A2, 2009 ;
Location in patent: Page/Page column 8-9 ;
反应条件
in dichloromethane T=0 - 40°C; 18 h; Product distribution / selectivity;
参考文献
US2005/159398 A1, ;
Page/Page column 8 ;
反应条件
in dichloromethane T=35°C; 4 h;
参考文献
US2005/159398 A1, ;
Page/Page column 8 ;
反应条件
in dichloromethane; water T=20 - 22°C; 22 h; Product distribution / selectivity;
参考文献
US2007/117975 A1, ;
Page/Page column 16 ;