2-氨基-2-(4-溴苯基)乙酸合成路线 （共 7 条）
反应条件
1: With ammonium chloride in methanol; water T=20°C; Strecker amino acid synthesis; 24.3333 h; 2: With hydrogenchloride; water 72 h; Reflux;
参考文献
Nieto, Sonia; Sayago, Francisco J.; Laborda, Pedro; Soler, Tatiana; Cativiela, Carlos; Urriolabeitia, Esteban P.
Tetrahedron, 2011 , vol. 67, # 23 p. 4185 - 4191
反应条件
1: K2CO3 / benzyltriethylammonium chloride / acetonitrile / Heating 2: 20percent aq. KOH / methanol / 2 h / Ambient temperature View Scheme
参考文献
Landini, Dario; Penso, Michele
Journal of Organic Chemistry, 1991 , vol. 56, # 1 p. 420 - 423
反应条件
bromoisocyanuric acid monosodium salt; sulfuric acid T=0°C; 2 h; Further byproducts given;
参考文献
Yokoyama, Yuusaku; Yamaguchi, Tomotsugu; Sato, Masanori; Kobayashi, Eri; Murakami, Yasuoki; Okuno, Hiroaki
Chemical and Pharmaceutical Bulletin, 2006 , vol. 54, # 12 p. 1715 - 1719
参考文献
Wislicenus; Elvert
Chemische Berichte, 1908 , vol. 41, p. 4126
反应条件
1: With 4-(N,N-dimethlyamino)pyridine; triethylamine in 1,4-dioxane; water 3 h; 2: With hydrogenchloride in 1,4-dioxane; water; ethyl acetate
参考文献
Niu, Huifeng
Patent: US2008/207563 A1, 2008 ;
Location in patent: Page/Page column 25 ;
反应条件
hydrogenchloride in water
T=20°C; 48 h;
参考文献
DEVGEN N.V.
Patent: WO2007/6547 A1, 2007 ;
Location in patent: Page/Page column 36-37 ;
WO 2007/006547 A1
反应条件
thionyl chloride
T=20°C; 24 h; Cooling with ice;
参考文献
Nieto, Sonia; Sayago, Francisco J.; Laborda, Pedro; Soler, Tatiana; Cativiela, Carlos; Urriolabeitia, Esteban P.
Tetrahedron, 2011 , vol. 67, # 23 p. 4185 - 4191
