2-苯并噻吩-1(3H)-酮合成路线 （共 20 条）
参考文献
Prey; Kondler
Monatshefte fuer Chemie, 1958 , vol. 89, p. 505,507
反应条件
lithium tert-butylate multistep reaction: 1) THF, -60 deg C, 15 - 20 min; 2) THF, -60 deg C, 3 h; further Michael acceptors and thiophthalides; Product distributionMechanism;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 3 p. 309 - 316
反应条件
T=850°C; P=0.0015 Torr;
参考文献
Drewnowski, Tomasz; Lesniak, Stanislaw; Mloston, Grzegorz; Siedlecka, Renata; Skarzewski, Jacek
Helvetica Chimica Acta, 2006 , vol. 89, # 5 p. 991 - 999
反应条件
trifluoroacetic anhydride
参考文献
McDonald, Robert S.; Patterson, Patricia; Stevens-Whalley, Ann
Canadian Journal of Chemistry, 1983 , vol. 61, p. 1846 - 1852
反应条件
sodium hydrogensulfide; ethanol; hydrogen sulfide
T=180°C;
参考文献
Du Pont de Nemours and Co.
Patent: US2097435 , 1935 ;
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid; sodium hydrogencarbonate; thiourea
Yield given. Multistep reaction;
参考文献
Pal; Murty; Mal
Synthetic Communications, 1993 , vol. 23, # 11 p. 1555 - 1560
反应条件
hydrogenchloride in 1,4-dioxane
T=25°C; 18 h;
参考文献
McDonald, Robert S.; Patterson, Patricia; Stevens-Whalley, Ann
Canadian Journal of Chemistry, 1983 , vol. 61, p. 1846 - 1852
反应条件
in toluene
T=154 - 155°C; P=0.01 Torr; 32 h;
参考文献
Dowd, Paul; Weber, William
Journal of Organic Chemistry, 1982 , vol. 47, # 24 p. 4777 - 4779
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene
T=100°C; 5 h;
参考文献
Ryu, Ilhyong; Okuda, Tohru; Nagahara, Kiyoto; Kambe, Nobuaki; Komatsu, Mitsuo; Sonoda, Noboru
Journal of Organic Chemistry, 1997 , vol. 62, # 22 p. 7550 - 7551
反应条件
1: 95 percent / ethanol / 5 h / Heating
2: 80 percent / 1percent NaOH / benzene; H2O / 1 h / Ambient temperature
View Scheme
参考文献
Kagabu, Shinzo; Kaku, Itone
Bioscience, Biotechnology, and Biochemistry, 1993 , vol. 57, # 11 p. 1899 - 1901
